Affinity DataIC50: 0.00300nMAssay Description:Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00600nMAssay Description:Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0180nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Agonistic activity at kappa opioid receptor of rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0410nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0410nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Evaluated for inhibitory activity against Opioid receptor kappa 1 of rabbit vas deferens (RVD)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:For antagonist experiments, protein was preincubated with test compounds for 15 min prior to the addition of 100 nM U69,593 and [35S]GTPγS. Reac...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Opioid receptor kappa 1 agonist potency was determined in vitro using rabbit vas deferens (LVD) preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.132nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 0.148nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 0.155nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 0.157nMAssay Description:The measurement of opioid receptor binding affinity was conducted using a radioligand binding assay on the membranes prepared from HEK293 cells (huma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Agonistic activity at kappa opioid receptor of rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 assessed as inhibition forskolin-induced cAMP accumulation after 15 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.253nMAssay Description:The measurement of opioid receptor binding affinity was conducted using a radioligand binding assay on the membranes prepared from HEK293 cells (huma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.255nMAssay Description:The measurement of opioid receptor binding affinity was conducted using a radioligand binding assay on the membranes prepared from HEK293 cells (huma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Antagonist activity at GAL4-VP16-fused KOR (unknown origin) expressed in human U2OS cells co-expressing Tango-OPRK1-BLA assessed as inhibition of U-5...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:The measurement of opioid receptor binding affinity was conducted using a radioligand binding assay on the membranes prepared from HEK293 cells (huma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:For antagonist experiments, protein was preincubated with test compounds for 15 min prior to the addition of 100 nM U69,593 and [35S]GTPγS. Reac...More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:For antagonist experiments, protein was preincubated with test compounds for 15 min prior to the addition of 100 nM U69,593 and [35S]GTPγS. Reac...More data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Antagonist activity at GAL4-VP16-fused KOR (unknown origin) expressed in human U2OS cells co-expressing Tango-OPRK1-BLA assessed as inhibition of U-5...More data for this Ligand-Target Pair
Affinity DataIC50: 0.537nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in mouse HN9.10 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Antagonist activity at GAL4-VP16-fused KOR (unknown origin) expressed in human U2OS cells co-expressing Tango-OPRK1-BLA assessed as inhibition of U-5...More data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair